Core Facilities at UNC

Below is a comprehensive list of all active research core facilities at UNC. These cores are administered by various schools, units, and departments across campus.

Use the “Select Core Category” function to filter cores by category or use the “Search” bar below to search for keywords and/or equipment. Click on column headers to sort by core name, contact information, or core category.

Are you a UNC core facility and would like to update or add information? Contact RCD@unc.edu and we’ll be happy to update your information on this page.

Select Core Category

This search function is limited to the core category selected. To search across all cores, make sure “All Cores” is selected in the “Select Core Category” to the left.

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Core Lab The ATPAC core lab uses analytical chemistry and pharmacologic infrastructure to support the translational development of drugs, anticancer agents, carrier-mediated agents and biologics.	Robert St. Claire Email: rstclaire@unc.edu Phone: Please email.	Analytical Chemistry	Translational Oncology and Nanoparticle Drug Development pharmacologic infrastructure translational development of drugs, anticancer agents, carrier-mediated agents and biologics pharmacokinetic (PK) and pharmacodynamic (PD); efficacy and toxicity], and biomarker studies LC-MS assay development small molecule therapeutics to complex drugs such as monoclonal antibodies, drug conjugates and polymers formulation development and CMC studies, assistance in PK/PD study design, LC-MS/MS or ICP-MS assay development, quantification of drugs from biological samples, PK/PD	Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Core Lab
Center for AIDS Research - Clinical Pharmacology and Analytical Chemistry Core € The Clinical Pharmacology and Analytical Chemistry (CPAC) Core facilitates the development of safe, effective strategies for HIV prevention, treatment, and cure. To achieve this goal, the CPAC Core provides expertise in small molecule drug development to assist investigators in nearly all aspects of HIV pharmacology research. This full-spectrum support, unique to our Core facility, helps advance preclinical and clinical HIV research towards ending the HIV epidemic.	Mackenzie Cottrell Email: mlcottre@email.unc.edu Phone: (919) 843-0321	Drug Development	#N/A	Center for AIDS Research - Clinical Pharmacology and Analytical Chemistry Core €
NMR Core Laboratory - Chemistry The Chemistry Department's Nuclear Magnetic Resonance (NMR) Core Laboratory provides training and access to NMR spectroscopy. We also participate in NMR investigations of chemical samples, prepare samples and acquire data.	Marc ter Horst Email: terhorst@unc.edu Phone: (919) 843-5802	Analytical Chemistry	Bruker Avance III HD 600 MHz NMR Spectrometer; Bruker Avance III HD 800 MHz NMR Spectrometer; Bruker Avance III HD 850 MHz NMR Spectrometer; Bruker Avance III HD 900 MHz NMR Spectrometer	NMR Core Laboratory - Chemistry
X-Ray Crystallography Core Laboratory (XCL) XCL primarily functions as a service crystallographic facility for the University and are actively collaborating with Department of Chemistry, Inorganic, Organic, and Material Division, Physics and Astronomy, biology, as well as the School of Pharmacy and the School of Medicine.	Chun-Hsing (Josh) Chen Email: joshchen@email.unc.edu Phone: (919) 962-1689	Analytical Chemistry	X-ray diffraction machines: Rigaku MicroMax-007 HF, Bruker D8 Venture Cryocrystallography equipment: Oxford Instruments Cryostream, MiTeGen MicroMount Data analysis software: CCP4, XtalView Protein expression and purification equipment: Ni-NTA columns, protein gel electrophoresis systems	X-Ray Crystallography Core Laboratory (XCL)

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Animal Clinical Chemistry Core The Animal Clinical Laboratory Services Core provides hematological and clinical chemistry testing as well as multiplexed biomarker immunoassays.	Greg Wilkerson Email: gwilker@email.unc.edu Phone: (919) 966-3653	Animal Husbandry, Surgery and Phenotyping	Hematology analyzers: Sysmex XS-10i automated hematology analyzer, Beckman Coulter LH 780 automated hematology analyzer Clinical chemistry analyzers: Abbott Architect c8000 clinical chemistry analyzer, Roche Cobas 6000 clinical chemistry analyzer Coagulation analyzers: STA-R Evolution coagulation analyzer Clinical microbiology equipment: BD BACTEC MGIT 960 automated blood culture system, BD Phoenix MGP automated microbiology panel system Nikon Eclipse E600 microscope, Leica DM700B microscope	Animal Clinical Laboratory Services
Animal Models Core We offer production, validation and use of CRISPR/Cas9 custom nucleases for production of mutant mice, rats or cell lines! As an early adopter of CRISPR/Cas9 technology, we have developed deep expertise in the use of CRISPR/Cas9 nucleases for genome editing. Contact us today to discuss your project needs.	Dale Cowley Email: dcowley@med.unc.edu Phone: (919) 843-9125	Animal Husbandry, Surgery and Phenotyping	animal housing facility: Isocage SPF cages, HEPA-filtered air, negative pressure ventilation Genetic modification equipment: Electroporators, CRISPR-Cas9 reagents, microinjection Animal imaging Animal behavior testing equipment: Open field mazes, Morris water mazes, rotarod systems	Animal Models Core
Animal Models Core - Marsico Lung Institute The Marsico Lung Institute/UNC Cystic Fibrosis Center Animal Models Core is dedicated to providing access and specialized expertise to conduct in vivo studies with animal models (primarily mouse) that provide insights into pulmonary disease pathophysiology and treatment.	Wanda O'Neal Email: woneal@med.unc.edu Phone: (919) 843-1097	Animal Husbandry, Surgery and Phenotyping	Taconic Biosciences IVIS Spectrum Imaging System Harvard Apparatus Mouse Phenotyping System Bio-Rad ChemiDoc MP Imaging System Bio-Rad CFX Connect Real-Time PCR System	Animal Models Core - Marsico Lung Institute
Cardiovascular Physiology and Phenotyping Core (CPPC) - McAllister Heart Institute We provide surgical, imaging and functional assessment services with a focus on cardiovascular system in rodents.	Aung Moe Zaw Email: aung-moe_zaw@med.unc.edu Phone: (919) 966-3036	Animal Husbandry, Surgery and Phenotyping	GE Vivid E95 Echocardiography GE Marquette treadmill GE Marquette blood pressure monitors Vascular Doppler imager Microvascular function analyzer	Cardiovascular Physiology and Phenotyping Core (CPPC) - McAllister Heart Institute
Large Animal Models Core (Center for Gastrointestinal Biology and Disease) The Large Animal Models Core was established because in vitro cell culture systems or small animal models have not always translated well to solving human health problems. The core was designed to provide models of digestive disease that are more pathophysiologically similar to humans.	Anthony Blikslager Email: Anthony_Blikslager@ncsu.edu Phone: (919) 513-7725	Animal Husbandry, Surgery and Phenotyping	housing and surgical facilities anesthesia, monitoring, and treatment large animal models of gastrointestinal diseases	Large Animal Models Core (Center for Gastrointestinal Biology and Disease)
Metabolic Phenotyping (NORC GEM and NRI) Metabolic Phenotyping offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease.	Raz Shaikh Email: shaikhsa@email.unc.edu Phone: (919) 843-4348	Animal Husbandry, Surgery and Phenotyping	Indirect calorimetry systems: Sable Systems Metabolic Cabinets intake monitoring Tecniplast Tecnal Metabolic cages PhenoMaster Animal activity monitors: Actiwatch 2 activity monitors	Metabolic Phenotyping (NORC GEM and NRI)
Mouse Behavioral Phenotyping Core (Carolina Institute for Developmental Disabilities) The Mouse Behavior Core provides investigators within the CIDD and throughout the UNC research community with a wide variety of behavioral tasks for studies in genetic, environmental, and pharmacological models of human disorders, and for preclinical efficacy testing of novel therapeutic agents.	Sheryl Moy Email: sheryl_moy@med.unc.edu Phone: (919) 966-3082	Animal Husbandry, Surgery and Phenotyping	Automated activity monitoring systems for tracking animal movement and behavior Maze and open field systems for assessing spatial learning and memory measuring sensory and motor functions in mice animal	Mouse Behavioral Phenotyping Core (Carolina Institute for Developmental Disabilities)
Mutant Mouse Resource and Research Center (MMRRC) The MMRRC at UNC distributes and cryopreserves scientifically valuable, genetically engineered mouse models of human development and disease to serve the biomedical research community. Since 1999 we have served as a member of an NIH funded national network of breeding and distribution facilities plus an information coordinating center serving together as NIH’s premier repository of spontaneous and induced mutant mouse and cell lines. The MMRRC aims to protect and enhance the mouse models, make them more accessible, and to support rigor and reproducibility in animal models research. Our mission also includes innovative research designed to enhance the resource.	Jackie Brooks Email: mmrrc_service@med.unc.edu Phone: (919) 966-8228	Animal Husbandry, Surgery and Phenotyping	Illumina NextSeq 2000 DNA Sequencer Thermo Fisher Scientific QuantStudio 7 Pro Real-Time PCR System Agilent 2100 Bioanalyzer Mouse Phenotyping System	Mutant Mouse Resource and Research Center (MMRRC)
National Gnotobiotic Rodent Resource Center - Gnotobiotic Core (Center for Gastrointestinal Biology and Disease) The Gnotobiotic Core at The University of North Carolina at Chapel Hill maintains several inbred and outbred strains of germ-free and gnotobiotic rodents. Our mission is to support animal model and basic research projects of CGIBD investigators and of scientists nationwide.	Josh Frost Email: josfrost@email.unc.edu Phone: (919) 843-8836	Animal Husbandry, Surgery and Phenotyping	Gnotobiotic isolators for rearing and maintaining animals in a sterile germ-free animal experiments gnotobiotic animal husbandry and research	National Gnotobiotic Rodent Resource Center - Gnotobiotic Core (Center for Gastrointestinal Biology and Disease)
Preclinical Research Unit PRU provides outstanding technical services and a seamless approach in working with the IACUC, DCM, and other core facilities on campus for labs that utilize small laboratory animals in their research. We offer technical expertise with small laboratory animal models for reproducibility of research.	Charlene Santos Email: csantos@unc.edu Phone: Please email.	Animal Husbandry, Surgery and Phenotyping	Animal housing and husbandry Cages and bedding Food and water dispensers Waste disposal Scalpels Sutures Anesthesia Ventilators X-ray Ultrasound MRI	Preclinical Research Unit
Radiation Core Facility Our mission is to provide radiation support for various research applications. We will provide safe and effective radiation service using various irradiators that are dedicated for research studies.	Hong Yuan Email: yuanh@med.unc.edu Phone: (919) 843-3813	Animal Husbandry, Surgery and Phenotyping	X-ray generators: Varian Clinac 2100, Elekta Synergy Linear accelerators: Varian TrueBeam, Elekta Infinity Brachytherapy equipment: Elekta HDR, Varian GammaMed Plus	Radiation Core Facility
Systems Genetic Core Facility Our core provides Collaborative Cross mice and genotypes to investigators both at UNC Chapel Hill and at other institutions.	Darla Miller Email: millerdr@med.unc.edu Phone: (919) 843-6471	Animal Husbandry, Surgery and Phenotyping	Illumina Infinium arrays, Affymetrix GeneChip arrays Genetic mapping QTL mapping software: Cartographer, HAPPY, MultiQTL Gene expression analysis equipment: Affymetrix GeneChip scanners, NanoString nCounter platform RNA-sequencing equipment: Illumina HiSeq 2500, Illumina NovaSeq 6000 Bioinformatics software: Partek Genomics Suite, DNAnexus, Galaxy	Systems Genetic Core Facility

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Center for AIDS Research - Biostatistics Core (F) The purpose of the CFAR Biostatistics Core is to accelerate successful HIV/AIDS research by direct provision of biostatistical support and by arranging mutually beneficial collaborations between CFAR researchers and statistical scientists.	Michael Hudgens Email: mhudgens@bios.unc.edu Phone: (919) 966-7253	Bioinformatics and Biostatistics	0	Center for AIDS Research - Biostatistics Core (F)
Research Computing Network Our Department of Biostatistics is recognized as a worldwide leader in research and practice. Members of our faculty are interested both in the development of statistical methodology and application of biostatistics in applied research.	Wesley Winkelman Email: wwinkelm@email.unc.edu Phone: (919) 966-7291	Bioinformatics and Biostatistics	High-performance computing (HPC) cluster: Dell PowerEdge servers, NVIDIA GPUs Data storage and management systems: NetApp storage arrays, Hadoop clusters Cloud computing services: Amazon Web Services (AWS), Microsoft Azure	Research Computing Network
Data Science Core (Carolina Institute for Developmental Disabilities) The overall objectives of this core are to enhance the productivity of CIDD investigators and the quality of their research. The core can assist IDDRC projects with study design, data management, as well as statistical and bioinformatics analyses.	Yun Li Email: yun_li@med.unc.edu Phone: (919) 843-2832	Bioinformatics and Biostatistics	High-performance computing (HPC) cluster: thousands of CPU cores, terabytes of memory Bioinformatics software: Genome Analysis Toolkit (GATK), Samtools, FASTQC, R/Bioconductor Data visualization and analysis tools: Tableau, Python matplotlib, Galaxy	Data Science Core (Carolina Institute for Developmental Disabilities)
Bioinformatics and Analytics Research Collaborative (BARC) We are a multi disciplinary center that aims to provide bioinformatics expertise and analysis to researchers across the university and beyond for high throughput data. We analyze, visualize, interpret, and manage big data while also offering custom solutions to fit our researchers’ needs.	Tyler Cook Email: Tyler_cook@med.unc.edu Phone: 9194450871	Bioinformatics and Biostatistics	High-performance computing cluster: thousands of CPU cores, terabytes of memory Bioinformatics software: Genome Analysis Toolkit (GATK), Samtools, FASTQC, R/Bioconductor Data visualization and analysis tools: Tableau, Python matplotlib, Galaxy	Bioinformatics and Analytics Research Collaborative (BARC)
Biostatistics Computer Services The service center enables our biostatisticians to perform the following services for sponsored research on campus: statistical simulations, symbolic mathematic computation, and data analysis, all using specialized software.	Wesley Winkelman Email: wwinkelm@email.unc.edu Phone: (919) 966-7291	Bioinformatics and Biostatistics	Linux clusters, servers, workstations Statistical software: SAS, R, STATA, SPSS Consultation	Biostatistics Computer Services
R. L. Juliano Structural Bioinformatics Core We provide consultations and collaborations on research studies requiring computational structural biology methods. Analyses available are not limited to the study of static structures, but also include molecular dynamics studies.	Venkata Chirasani Email: venkatr@med.unc.edu Phone: (919) 966-5044	Bioinformatics and Biostatistics	Rosetta, Amber, VMD Structural biology software Molecular graphics software: PyMOL, Chimera Bioinformatics analysis software: BLAST, ClustalW, HMMER	R. L. Juliano Structural Bioinformatics Core
Biostatistics Core (Center for Gastrointestinal Biology and Disease) Our core provides an interface between basic scientists, clinical researchers, and informatics specialists to support translational research.	Amy Smither Email: amy_smither@med.unc.edu Phone: (919) 966-8381	Bioinformatics and Biostatistics	Statistical software: SAS, R, STATA, SPSS high-performance computing resources statistical methods Biostatistics analysis Bioinformatics	Biostatistics Core (Center for Gastrointestinal Biology and Disease)
Biometric Consulting Laboratory The Biometric Consulting Laboratory, a component of the Department of Biostatistics at the UNC Gillings School of Global Public Health, provides collaborative biostatistical consultation for study design and data analysis for investigators.	Gary Koch Email: bcl@bios.unc.edu Phone: (919) 966-7282	Bioinformatics and Biostatistics	Statistical software: SAS, R, STATA, SPSS computing statistical Biostatistics Bioinformatics methodology analysis Consultation	Biometric Consulting Laboratory

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
BioSpecimen Processing Facility The Facility provides laboratory support for investigator-initiated large-scale clinical, epidemiologic, and other studies and functions as a human biospecimen repository. It also serves as a resource for clinicians who wish to store and study samples from unusual or potentially important patients.	Patricia Basta Email: patricia_basta@unc.edu Phone: (919) 843-3860	Biospecimen Collection and Processing	centrifuges, homogenizers, freezers, incubators storage equipment: freezers, biorepositories specimen collection, processing, and storage	BioSpecimen Processing Facility
Center for AIDS Research - HIV/STD Laboratory Core (J) The HIV/STD Laboratory Core of the UNC CFAR offers services and collaborations to HIV researchers for their basic and clinical research projects. The Core provides a GCLP environment for specimen processing and testing. The HIV/STD Laboratory Core consults and collaborates with researchers at UNC-CH, RTI International, and FHI 360 (as well as outside researchers).	Kristina de Paris Email: abelk@med.unc.edu Phone: (919) 843-9560	Biospecimen Collection and Processing	0	Center for AIDS Research - HIV/STD Laboratory Core (J)

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Core Lab The ATPAC core lab uses analytical chemistry and pharmacologic infrastructure to support the translational development of drugs, anticancer agents, carrier-mediated agents and biologics.	Robert St. Claire Email: rstclaire@unc.edu Phone: Please email.	Analytical Chemistry	Translational Oncology and Nanoparticle Drug Development pharmacologic infrastructure translational development of drugs, anticancer agents, carrier-mediated agents and biologics pharmacokinetic (PK) and pharmacodynamic (PD); efficacy and toxicity], and biomarker studies LC-MS assay development small molecule therapeutics to complex drugs such as monoclonal antibodies, drug conjugates and polymers formulation development and CMC studies, assistance in PK/PD study design, LC-MS/MS or ICP-MS assay development, quantification of drugs from biological samples, PK/PD	Advanced Translational Pharmacology and Analytical Chemistry (ATPAC) Core Lab
Center for AIDS Research - Clinical Pharmacology and Analytical Chemistry Core € The Clinical Pharmacology and Analytical Chemistry (CPAC) Core facilitates the development of safe, effective strategies for HIV prevention, treatment, and cure. To achieve this goal, the CPAC Core provides expertise in small molecule drug development to assist investigators in nearly all aspects of HIV pharmacology research. This full-spectrum support, unique to our Core facility, helps advance preclinical and clinical HIV research towards ending the HIV epidemic.	Mackenzie Cottrell Email: mlcottre@email.unc.edu Phone: (919) 843-0321	Drug Development	#N/A	Center for AIDS Research - Clinical Pharmacology and Analytical Chemistry Core €
Cystic Fibrosis Molecular/Functional Measurement Core The Cystic Fibrosis Molecular/Functional Measurement Core is designed to provide services to analyze the efficacy of treatments that target different stages in the pathogenic sequelae of CF disease development.	Martina Gentzsch Email: martina_gentzsch@med.unc.edu Phone: (919) 966-7058	Drug Development	PCR instruments for measuring gene expression Western blot equipment for analyzing protein expression cystic fibrosis research CF	Cystic Fibrosis Molecular/Functional Measurement Core
Nanomedicines Characterization Core Facility (NCore) NCore implements the Center for Nanotechnology in Drug Development (CNDD) mission of accelerating translation of new nanomedicines into clinic by providing comprehensive physicochemical characterization of nanoscale entities.	Marina Sokolsky Email: ncore@unc.edu Phone: (919) 962-4698	Drug Development	Malvern Panalytical Zetasizer Nano ZSP Zeta Potential Analyzer Malvern Panalytical DynaPro Plate Reader JEOL JEM-1400 Plus Transmission Electron Microscope Zeiss Supra 25 Field Emission Scanning Electron Microscope	Nanomedicines Characterization Core Facility (NCore)
NMR Facility -School of Pharmacy The UNC ESOP NMR Facility serves users from inside and outside the University. The lab has been used to study small molecules and natural products; polymers; and biomolecular structure and dynamics. The facility houses a fully automated 400MR, as well as Inova 500 and Inova 400 spectrometers.	Nelson Zhao Email: czhao1@unc.edu Phone: (919) 962-0060	Drug Development	Nuclear magnetic resonance (NMR) spectrometers (up to 600 MHz): Bruker Avance III 600, Varian Inova 600 Cryogenics equipment: liquid helium dewars, superconducting magnets NMR data analysis software: NMRPipe, TopSpin	NMR Facility -School of Pharmacy

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
BeAM Design Innovation Hub We facilitate and complement research of all types by providing engineering consultation, design, fabrication, assembly, and select repair services in a wide range of disciplines.	Glenn W. Walters Email: walters@unc.edu Phone: (919) 966-3531	Fabrication, Nanofabrication, and Engineering	3D Systems ProJet 660Pro; Epilog Fusion Pro 48 Laser Cutter; Epilog Fusion Pro 48 Laser Cutter; MakerBot Replicator 2X	BeAM Design Innovation Hub
Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE) Our mission is to develop molecule/material hybrid photoelectrodes for cooperative sunlight-driven generation of liquid fuels from carbon dioxide, nitrogen, and water.	Renato Neiva Sampaio Email: renatons@email.unc.edu Phone: (919) 962-6320	Fabrication, Nanofabrication, and Engineering	photoreactors, electrochemistry workstations, spectrometers photocatalysts photocatalytic systems for solar energy conversion photocatalysis, solar energy conversion, materials chemistry	Center for Hybrid Approaches in Solar Energy to Liquid Fuels (CHASE)
Chapel Hill Analytical and Nanofabrication Laboratory (CHANL) CHANL enables cutting edge research by providing equipment, expertise and training for nano/micro fabrication and characterization in an open-access facility with capabilities not otherwise available on campus.	Bob Geil Email: bob.geil@unc.edu Phone: (919) 843-6555	Fabrication, Nanofabrication, and Engineering	FEI Helios NanoLab 660 DualBeam; FEI Tecnai G2 Spirit BioTWIN; Nikon Eclipse Ti-E Inverted Microscope; Oxford Instruments PlasmaPro System 100 Cobra ICP-RIE; Oxford Instruments PlasmaPro System 100 ICP-RIE; Oxford Instruments PlasmaPro System 100 PECVD; Oxford Instruments PlasmaPro System 100 RIE; Oxford Instruments PlasmaPro System 100 Sputter; Veeco Dimension Icon Atomic Force Microscope	Chapel Hill Analytical and Nanofabrication Laboratory (CHANL)
Chemistry Electronics Facility We provide design and repair services on the UNC campus. Capabilities include analog, digital, and RF design as well as signal processing and software development. We also provide circuit simulation, mathematical modeling, and mechanical design in support of prototype production and construction.	Collin McKinney Email: collin@unc.edu Phone: (919) 843-5801	Fabrication, Nanofabrication, and Engineering	Electronics fabrication equipment for building custom circuits and devices electronics design, fabrication, and characterization	Chemistry Electronics Facility
Glass Shop The Glass Shop is a full service shop primarily engaged in the design and fabrication of specialized scientific glassware as well as repairs and modifications of existing glassware.	Mark Wicker Email: mmwicker@email.unc.edu Phone: (919) 966-1229	Fabrication, Nanofabrication, and Engineering	0	Glass Shop

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Flow Cytometry Core Facility The UNC Flow Cytometry Core Facility (FlowCore) provides state-of-the-art flow cytometry services to the entire UNC-CH research community as well as to others in the Research Triangle Park area.	Ramiro Diz Email: ramiro_diz@med.unc.edu Phone: (919) 966-7812	Cytometry	cytometers and four cell sorters flow cytometry data Cell sorting Intracellular staining Cytokine analysis Apoptosis Cell cycle	Flow Cytometry Core Facility
Vector Core The Vector Core at the University of North Carolina at Chapel Hill (UNC Vector Core) was founded in 1993 as a full-service viral vector production organization. We have extensive experience in manufacturing research grade vectors utilize our unique expertise to ensure your project is on time and on budget. Our goal is to deliver the highest quality AAV vectors to our academic, government, foundation, and biotech industry clients.	Xinghua Zeng Email: xhzeng@med.unc.edu Phone: (919) 445-0338	Vector Production	Molecular biology equipment: PCR machines, gel electrophoresis systems, centrifuges DNA cloning Plasmid kits, restriction enzymes, ligases Cell transfection equipment: Electroporators, lipofectamine reagents Viral vector production equipment: Bioreactors, cell culture equipment Viral vector analysis equipment: ELISA kits, flow cytometry analyzers	Vector Core

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Advanced Analytics Core (Center for Gastrointestinal Biology and Disease) We provide high-quality, quantitative solutions for studying proteins and nucleic acids at the bulk or single-cell level.	Carlton Anderson Email: canderson@med.unc.edu Phone: (919) 260-3461	Genetics and Genomics	Agilent 2100 Bioanalyzer; Agilent TapeStation 4200; Bio-Rad CFX96 Touch Real-Time PCR Detection System; Bio-Rad S3e Cell Sorter; Luminex MAGPIX; NanoString nCounter; Thermo Fisher Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer	Advanced Analytics Core (Center for Gastrointestinal Biology and Disease)
Clinical Genomic Analysis (GENYSIS) Core We collaborate with the BioSpecimen Processing (BSP) facility, the High-Throughput Sequencing Facility (HTSF), and the McLendon Molecular Genetics Laboratory (MGL) to provide clinical researchers with four main services: Bioinformatics, Variant analysis, Clinical reporting, Post-test services.	GENYSIS Core (Dr. Tam P. Sneddon) Email: genysis@email.unc.edu Phone: (919) 966-4676	Human Research/Clinical Applications and Support, Genetics and Genomics	High-throughput sequencing platforms for analyzing DNA and RNA sequences Bioinformatics tools genomic data clinical genomics and genetic testing	Clinical Genomic Analysis (GENYSIS) Core
CRISPR Screening Facility CRISPR has supercharged the ability to conduct rapid and effective genetic and epigenetic screening.	CRISPR Staff (Brian Golitz) Email: crispr@unc.edu Phone: (919) 966-1307	Genetics and Genomics	CRISPR/Cas9 gene editing tools for creating targeted mutations in cells and organisms screening platforms for identifying cells with desired genetic modifications	CRISPR Screening Facility
Functional Genomics Core We provide researchers with high quality microarray data using Thermo Fisher expression and genotyping arrays.	Mike Vernon Email: mike_vernon@med.unc.edu Phone: (919) 445-2865	Genetics and Genomics	High-throughput DNA sequencing platforms genomic genomics RNA-seq ChIP-seq ATAC-seq Single-cell RNA-seq Epigenomics Metagenomics	Functional Genomics Core
High Throughput Sequencing Facility We offer comprehensive library services, NextGen sequencing and alternative technologies including long reads. We also provide technological support to users to ensure maximum data value. Our goal is to help researchers make biological sense out of their data.	Piotr A Mieczkowski Email: Piotr_Mieczkowski@med.unc.edu Phone: (919) 962-4471	Genetics and Genomics	DNA sequencers: Illumina HiSeq X Ten, Illumina NovaSeq 6000 Bioinformatics software: Galaxy, bcl2fastq, FastQC, Trimmomatic, STAR, RSEM	High Throughput Sequencing Facility
Homologous Recombination Center	Beverly Koller Email: bkoller@email.unc.edu Phone: (919) 966-0508	Genetics and Genomics	Gene editing Bioinformatics	Homologous Recombination Center
Immune Monitoring and Genomics Facility We provide investigators with cellular immunology, molecular immunology, and immunogenomics services that can delineate interactions between the immune system and tumor tissues.	Karen McKinnon Email: kmck@med.unc.edu Phone: (919) 843-6080	Genetics and Genomics	Flow cytometers: BD FACSAria II, BD FACSCalibur Mass spectrometers: Agilent 6460 Triple Quad, Sciex Q5500 Bioinformatics software: FlowJo, Cytobank, Galaxy IMGF	Immune Monitoring and Genomics Facility
Kinase Chemogenomic Set (KCGS) Sales The scientific focus of the SGC-UNC is the chemical biology of the dark proteome. Our scientists are working to create chemical inhibitors and screening assays to explore the biology of these understudied proteins from the human genome in health and disease. Scientists at the SGC-UNC are experts in medicinal chemistry, cell biology, and chemical biology. They are using these skills to develop small molecule inhibitors of dark proteins to be used in cells to reveal their biology.	Tim Willson Email: tim.willson@unc.edu Phone: (919) 491-3177	Genetics and Genomics	library of kinase inhibitors dark	Kinase Chemogenomic Set (KCGS) Sales
Mammalian Genotyping Core Our mission is to support population, basic, clinical and translational research by providing centralized cost-efficient, high quality genotyping and methylation services.	Amanda Gerringer, MSFS Email: ajhoff@email.unc.edu Phone: (919) 445-4771	Genetics and Genomics	Applied Biosystems QuantStudio 7 Pro Real-Time PCR System Thermo Fisher Scientific KingFisher Flex Magnetic Particle Processor Agilent Bioanalyzer 2100 Qubit 4 Fluorometer Eppendorf Mastercycler Nexus Gradient PCR System	Mammalian Genotyping Core
Microbiome Core We provide the research community with the facilities and expertise to characterize complex microbial communities and microbial interactions.	Microbiome Core Email: microbiome@med.unc.edu Phone: (919) 962 3569	Genetics and Genomics	Illumina MiSeq NGS Agilent Bravo Automated Liquid Handling System Bio-Rad CFX96 Real-Time PCR Eppendorf Mastercycler Nexus Gradient PCR Thermo Fisher Scientific NanoDrop One Spectrophotometer	Microbiome Core
Nutrigenomics (NORC GEM) We provide investigators with the expertise and resources necessary to investigate the role of host genetic factors in biological responses to nutritional exposure.	Saroja Voruganti Email: saroja@unc.edu Phone: (704) 250-5009	Genetics and Genomics	Real-time PCR machines: Bio-Rad CFX96 Touch Real-Time PCR System Microarray scanners: Affymetrix GeneChipScanner 3000 DNA sequencing machines: Illumina HiSeq 2500 Bioinformatics software: Partek Genomics Suite, DNAnexus	Nutrigenomics (NORC GEM)
Translational Genomics Lab (TGL) - LCCC The UNC Lineberger Comprehensive Cancer Center Translational Genomics Lab (TGL) is a high-throughput core facility established in 2011 to provide comprehensive genomic services for investigators. TGL performs sample processing and analyses for the molecular, pathologic, and genomic characterization of patient-derived specimens in preclinical research projects and clinical protocols. Service offerings include nucleic acid extraction and quality control, gene expression profiling, single cell genomics, spatial genomics, next-generation sequencing (NGS) library preparation, and high-throughput sequencing.	Adam D. Pfefferle Email: adamp@email.unc.edu Phone: (919) 962-8324	Genetics and Genomics	Illumina NovaSeq 6000 Illumina NextSeq 2000 PacBio Sequel II Oxford Nanopore Technologies MinION Oxford Nanopore Technologies MinION Agilent Bioanalyzer 2100 Qubit 4 Fluorometer Thermo Scientific Kingfisher Flex Magnetic Particle Processor Beckman Coulter Allegra X-15R Centrifuge Eppendorf Mastercycler Nexus Gradient PCR System	Translational Genomics Lab (TGL) - LCCC
Vironomics Core Facility The Vironomics Core is led by our Principal Investigator, Dr. Dirk Dittmer, and includes several research staff. Our facilities are located on the 1st floor of the Lineberger Cancer Center (wing parallel with West Dr). The main research focus of the Dittmer lab is understanding viral tumorigenesis, especially that associated with Kaposi’s Sarcoma Herpesvirus (KSHV).	Dirk Dittmer Email: vironomics@med.unc.edu Phone: (919) 843-5292	Genetics and Genomics	Viral RNA/DNA extraction equipment: QIAamp Viral RNA Mini Kit, MagNA Pure 96 Nucleic Acid Isolation Kit Viral sequencing equipment: Illumina MiSeq, Illumina HiSeq Xten Bioinformatics software: CLC Genomics Workbench, Geneious Prime Virus isolation and propagation equipment: Cell culture trays, flasks, pipettes	Vironomics Core Facility

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Histology Core (Center for Gastrointestinal Biology and Disease) The Cell Services & Histology Core provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. Consultations are also available. The core also offers image analysis through the Translational Pathology Laboratory. These services are available to CGIBD members and non-members.	Carolyn Suitt Email: carolyn_suitt@med.unc.edu Phone: (919) 966.1757	Histology / Pathology	Consultations: advice on tissue preparation, staining methods, and interpretation of results Histology services: routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry analysis of histological images	Histology Core (Center for Gastrointestinal Biology and Disease)
Histology Research Core Welcome to the Histology Research Core where we serve the histology needs of the UNC community and beyond. We have experience with various organisms including, but not limited to mouse, rat, pig, cat, dog, fish, human and primate. Additionally, we have provided histology services for plants and invertebrates such as coral, caterpillars and even stinkbugs!	Ashley Ezzell Email: jezzell@email.unc.edu Phone: (919) 966-1202	Histology / Pathology	Tissue processing equipment: Leica Microsystems HistoCore Embedding Station, Thermo Scientific Microm HM350 Paraffin Microtome Histochemistry equipment: Thermo Scientific Shandon Cytospin 4 Cytocentrifuge, Thermo Scientific Shandon Cytolyt Solution, Zeiss Axioskop 40 Microscope Immunohistochemistry equipment: Dako Autostainer Link 42, Leica Biosystems Bond-Max Automated IHC System, Leica Biosystems Leica DM7000 Microscope Microscopy equipment: Nikon Eclipse Ti2 Inverted Microscope, Leica Biosystems Leica DMi8 Automated Microscope	Histology Research Core
Pathology Services Core We provide high quality, comprehensive pathology services for pre-clinical and clinical studies.	Gaby De la Cruz Email: gdelacruz@med.unc.edu Phone: (919) 966-9620	Histology / Pathology	Histopathology Leica Microsystems HistoCore Embedding Station Thermo Scientific Microm HM350 Paraffin Microtome Leica Biosystems Leica DMi8 Automated Microscope Stains and reagents for tissue processing and staining Cytology Thermo Scientific Shandon Cytospin 4 Cytocentrifuge Thermo Scientific Shandon Cytolyt Solution Zeiss Axioskop 40 Microscope Stains and reagents for cell preparation and staining Immunohistochemistry Dako Autostainer Link 42 Leica Biosystems Bond-Max Automated IHC System Leica Biosystems Leica DM7000 Microscope Antibodies and reagents for immunohistochemical staining	Pathology Services Core

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Animal Clinical Chemistry Core The Animal Clinical Laboratory Services Core provides hematological and clinical chemistry testing as well as multiplexed biomarker immunoassays.	Greg Wilkerson Email: gwilker@email.unc.edu Phone: (919) 966-3653	Animal Husbandry, Surgery and Phenotyping	Hematology analyzers: Sysmex XS-10i automated hematology analyzer, Beckman Coulter LH 780 automated hematology analyzer Clinical chemistry analyzers: Abbott Architect c8000 clinical chemistry analyzer, Roche Cobas 6000 clinical chemistry analyzer Coagulation analyzers: STA-R Evolution coagulation analyzer Clinical microbiology equipment: BD BACTEC MGIT 960 automated blood culture system, BD Phoenix MGP automated microbiology panel system Nikon Eclipse E600 microscope, Leica DM700B microscope	Animal Clinical Laboratory Services
Respiratory TRACTS Core (RTC) We provide turnkey services to clinical and biomedical investigators at the University of North Carolina at Chapel Hill as well as off-site investigators.	Mandy Bush Email: mbush43@email.unc.edu Phone: (919) 537-3968	Immunoassay	Real-time PCR machines: Bio-Rad CFX96 Touch Real-Time PCR System, ThermoFisher QuantStudio 7 Flex Real-Time PCR System Microarray scanners: Affymetrix GeneChip Scanner 3000 DNA sequencing machines: Illumina HiSeq 2500 Bioinformatics software: Partek Genomics Suite, DNAnexus Luminex multiplex assay platform: Luminex MagPlex Multiplexing System NanoString nCounter analysis system: NanoString nCounter MAX platform Cell culture equipment: CO2 incubators, laminar flow hoods, centrifuges ELISA plate readers: BioTek Synergy H1 Microplate Reader, Thermo Scientific Multiscan FC Microplate Photometer	Respiratory TRACTS Core (RTC)

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Atomic Absorption Spectrometry Lab The Atomic Absorption Spectrometry Lab provides analysis that is used to determine the levels of arsenate, methylated and other organic forms of arsenic in solutions and/or matrices.	Mirek Styblo Email: styblo@med.unc.edu Phone: (919) 966-5721	Metabolomics, Proteomics, and Mass Spectrometry	PerkinElmer AAnalyst 800	Atomic Absorption Spectrometry Lab
Biomarker Mass Spectrometry Core Facility Our core provides expertise for qualitative and quantitative analysis of a variety of biomarkers using liquid chromatography and mass spectrometry instrumentation.	Zhenfa Zhang Email: zhenfaz@email.unc.edu Phone: (919) 966-2664	Metabolomics, Proteomics, and Mass Spectrometry	Liquid chromatography-mass spectrometers (LC-MS): Agilent 6460 Triple Quad, Sciex Q5500 Gas chromatography-mass spectrometers (GC-MS): Agilent 7890A, Thermo Fisher Scientific TSQ 8000 Triple Quad	Biomarker Mass Spectrometry Core Facility
Mass Spectrometry Core Laboratory ATOMS We provide equipment, expertise and training in small molecule applications utilizing mass spectrometry in an open-access facility. We also support high-throughput catalysis research for inorganic and organic research labs in our Reaction Innovation Sub-Core for Excellence (RISE) Catalysis Center.	Brandie M. Ehrmann Email: behrmann@email.unc.edu Phone: (919) 962-6813	Metabolomics, Proteomics, and Mass Spectrometry	Thermo Fisher Scientific Orbitrap Eclipse Tribrid Mass Spectrometer Thermo Fisher Scientific Q Exactive Plus Mass Spectrometer Thermo Fisher Scientific TSQ Quantum Ultra Mass Spectrometer Agilent 6470 Triple Quadrupole Mass Spectrometer Shimadzu LC-20AD series HPLC fluorescence detection	Mass Spectrometry Core Laboratory ATOMS
Metabolomics and Exposome Laboratory Service Core (MEL) Metabolomics and Exposome Laboratory Service Core (MEL) encourages collaborations that promote the use of untargeted and broad spectrum metabolomics in basic, clinical, and translational research focused on environmental health and precision nutrition.	Susan Sumner Email: susan_sumner@unc.edu Phone: (704) 250-5066	Metabolomics, Proteomics, and Mass Spectrometry	Thermo Fisher Scientific Q Exactive HF-X Mass Spectrometer Agilent 6890N Gas Chromatograph with Mass Spectrometer Detection (GC-MS) Shimadzu LC-20AD series HPLC with Mass Spectrometer Detection (LC-MS)	Metabolomics and Exposome Laboratory Service Core (MEL)
Quantitative Targeted Proteomics (QTAP) Core The quantitative targeted proteomics (QTAP) core specializes in the quantification of proteins in biological matrices by LC-MS/MS. The core is newly established (2024) but the laboratory has been working on targeted proteomics for over fifteen years. Quantifications can be undertaken employing labeled standards (more accurate) or it can be label free (less accurate or relative). The analytical techniques employed by the core are nano- or microLC coupled to triple quadrupole mass spectrometry.	John Fallon Email: jfallon@email.unc.edu Phone: (919) 966-3787	Metabolomics, Proteomics, and Mass Spectrometry		Quantitative Targeted Proteomics
UNC Metabolomics and Proteomics (MAP) Core We provide services for the analysis of proteins from tissues, cells or other biological samples. We are available to the UNC community, as well as external customers worldwide. We’re committed to educating students and researchers in the field of proteomics.	Laura Herring Email: laura_herring@med.unc.edu Phone: (919) 966-4681	Metabolomics, Proteomics, and Mass Spectrometry	Thermo Fisher Scientific Orbitrap Eclipse Tribrid Mass Spectrometer Thermo Fisher Scientific Q Exactive Plus Mass Spectrometer Thermo Fisher Scientific LTQ Orbitrap Velos Mass Spectrometer Shimadzu LC-20AD series HPLC with Mass Spectrometer Detection (LC-MS)	UNC Metabolomics and Proteomics (MAP) Core

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
AHS DXA Imaging DXA is a unique imaging procedure that allows for the calculation and analysis of differential body tissues within a subject and allows for the collection of bone mineral density data. DXA imaging is performed by ARRT registered technologists trained in the rigors of clinical trial imaging and data collection.	Valerie Tan Email: vtan@med.unc.edu Phone: (919) 843-4828	Microscopy and Imaging	Dual energy X-ray absorptiometry (DEXA) scanner: Lunar PIXImus DEXA Bone mineral density (BMD) analysis software: Lunar Encore Plus software Body composition analysis software: Lunar Prodigy software Anthropometric measurement equipment: Height gauge, tape measure, skinfold calipers	AHS DXA Imaging
Biology Microscopy Core We provide the Department of Biology and broader UNC community with access, training and assistance with a wide array of high-end imaging systems, for epifluorescence, TIRF, confocal, spinning disk and super-resolution, as well as image analysis.	Nat Prunet Email: nprunet@unc.edu Phone: (919) 962-4398	Microscopy and Imaging	Confocal microscopes: Zeiss LSM 780, Leica DMi8 Fluorescence microscopes: Olympus BX51, Nikon Eclipse Ti2 Electron microscopes: FEI Tecnai G2, FEI Helios G3 FIB-SEM	Biology Microscopy Core
Biomedical Research Imaging Center (BRIC) We provide world-class clinical and preclinical imaging services to researchers within the University system and to researchers from institutions and companies in the surrounding area with cutting-edge imaging hardware such as PET/MR,PET/CT, MRI, SPECT, Optical Imaging, and Ultrasound.	Angela High Creighton Email: angela_creighton@med.unc.edu Phone: (919) 843-7666	Microscopy and Imaging	MRI systems: Siemens Skyra 3T, Philips Ingenia 3T CT scanners: GE Lightspeed VCT, Siemens Somatom Force PET scanners: GE Discovery PET/CT, Siemens Biograph mCT SPECT scanners: GE Discovery NM/CT 670 Pro Optical imaging systems: PerkinElmer Optima IV, Xenogen IVIS Spectrum	Biomedical Research Imaging Center (BRIC)
Hooker Imaging Core The Hooker Imaging Core (HIC) is an open core providing instrumentation, training and expertise in light and electron microscopy for the UNC biomedical research community and outside users.	Wendy Salmon Email: wendy_salmon@med.unc.edu Phone: (617) 429-0158	Microscopy and Imaging	Microscopes: Zeiss LSM 780 confocal microscope, Nikon Eclipse Ti2 fluorescence microscope Image analysis software: Fiji, Imaris, MetaMorph microscopy electron confocal spinning disk	Hooker Imaging Core
Image Storage and Analysis The Image Analysis Core Lab in the BRIC is devoted to the development of novel image analysis methods and tools, and their applications to various clinical research and trials. The developed methods include deformable registration (HAMMER), deformable segmentation (AFDM), and multivariate pattern classification algorithms.	BRIC Administration Email: bric_admin@med.unc.edu Phone: (919) 843-6194	Microscopy and Imaging	storing and archiving digital images Analysis software: Fiji, ImageJ, Imaris, MetaMorph	Image Storage and Analysis
Integrative Program for Biological and Genomic Sciences Microscopy IBGS at UNC operates at the interface between the UNC School of Medicine and College of Arts & Sciences to support research that works toward a mechanistic understanding of basic biological processes, thereby generating discoveries that fuel the translational research pipeline.	Robert (Bob) Duronio Email: duronio@med.unc.edu Phone: (919) 962-4568	Microscopy and Imaging	Confocal microscopes: Zeiss LSM 780, Leica DMi8 Fluorescence microscopes: Olympus BX51, Nikon Eclipse Ti2 Electron microscopes: FEI Tecnai G2, FEI Helios G3 FIB-SEM	Integrative Program for Biological and Genomic Sciences Microscopy
Microscopy Services Laboratory (MSL) We provide training, assistance and services in light microscopy, electron microscopy and image analysis.	Pablo Ariel Email: msl@med.unc.edu Phone: (919) 966-2413	Microscopy and Imaging	Zeiss LSM 900 Confocal Laser Scanning Microscope Zeiss LSM 710 Spectral Confocal Laser Scanning Microscope Lavision Ultramicroscope II light-sheet system Andor Dragonfly Spinning Disk Confocal Microscope Andor XD Spinning Disk Confocal Microscope JEOL JEM 1230 Transmission Electron Microscope Zeiss Supra 25 Field Emission Scanning Electron Microscope	Microscopy Services Laboratory (MSL)
Neuroscience Microscopy Core We provide access to high-resolution imaging technologies, implement new imaging technologies, related to real-time and tissue clearing based imaging of neurodevelopment and neural functions, and provides training, consultation, data analysis, image processing, and centralized technical expertise.	Michelle S. Itano Email: itano@unc.edu Phone: (919) 966-5807	Microscopy and Imaging	Zeiss LSM880, Nikon A1R Confocal laser scanning microscopy (CLSM) systems Two-photon microscopy systems: Bruker Aura, Leica TCS SP8 Scanning electron microscopy (SEM) systems: FEI Quanta 200, Zeiss Merlin Transmission electron microscopy (TEM) systems: FEI Tecnai G2 Spirit BioTwin, JEOL JEM 2100 Light sheet fluorescence microscopy (LSFM) systems: LaVision BioView 110, PerkinElmer UltraVIEW X Image analysis software: Fiji, ImageJ, Imaris	Neuroscience Microscopy Core
Radiochemistry Research Service Center The Radiochemistry facility contains all the equipment needed to support radiopharmaceutical development and production for molecular imaging studies. Production of the PET radioisotopes is accomplished with a high energy (16.5MeV) GE PETtrace cyclotron, multiple automated radiochemical processing modules, hot cells, and other ancillary equipment. The radiopharmacy production laboratory is under GMP conditions as required by the U.S. Pharmacopeia Chapter 823 and 21CFR part 212.	Angela Creighton Email: bric_admin@med.unc.edu Phone: (919) 843-6194	Microscopy and Imaging	Radioisotope production and handling equipment: cyclotrons, hot cells Radiolabeling equipment: fume hoods, glove boxes Radiochemistry analysis equipment: gamma counters, scintillation counters	Radiochemistry Research Service Center
Small Animal Imaging With Hyperpolarized Xe Gas Our lab performs various magnetic resonance imaging (MRI) experiments using hyperpolarized Xenon (HPXe) gas to look at the lungs of mouse models of cystic fibrosis.	Tamara Branca Email: rtbranca@unc.edu Phone: Please email.	Microscopy and Imaging	Hyperpolarized Xe gas production system	Small Animal Imaging With Hyperpolarized Xe Gas

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Biology Photolab The Department of Biology prints posters for personnel inside the University.	Brian Nalley Email: bnalley@bio.unc.edu Phone: (919) 962-2419	Other Cores at University of North Carolina at Chapel Hill	poster posters studies	Biology Photolab
Biology Plant Growth Facility The Biology Plant Growth Facility, a.k.a the Greenhouse. The Department of Biology rents bench space in the Greenhouse to University personnel as well as outside organizations.	Kate Palmer Email: katharine.palmer@med.unc.edu Phone: (919) 962-3454	Other Cores at University of North Carolina at Chapel Hill	Controlled-environment growth chambers Plant growth measurement equipment: leaf area meters, chlorophyll meters, PAR meters Photosynthesis measurement equipment: gas exchange analyzers, fluorescence meters	Biology Plant Growth Facility
Carolina Population Center Carolina Demography Carolina Demography	Nathan Dollar Email: ntdollar@unc.edu Phone: (919) 445-6911	Other Cores at University of North Carolina at Chapel Hill	0	Carolina Population Center Carolina Demography
Carolina Population Center Research IT Service Center CPC Research IT Service Center	Jamie Smith Email: jmsmith@med.unc.edu Phone: (919) 962-3646	Other Cores at University of North Carolina at Chapel Hill	0	Carolina Population Center Research IT Service Center
Center for AIDS Research Administrative Core (A) The Administrative Core supports and promotes the entire range of basic, clinical, prevention, social, behavioral, and translational HIV research activities throughout the UNC CFAR. It provides the interface with community and advocacy groups, including sponsoring a yearly HIV/AIDS care symposium and the World AIDS Day symposium.	Ronald Swanstrom Email: risunc@med.unc.edu Phone: (919) 966-5710	Other Cores at University of North Carolina at Chapel Hill	0	Center for AIDS Research Administrative Core (A)
Collagen Analysis Core This core provides laboratory analysis of: collagen content, amino acid analysis including collagen specific amino acids, reducible collagen cross-link analysis (including cross-link precursor aldehydes), and non-reducible collagen cross-link analysis (fluorescent and non-fluorescent cross-links).	Mitsuo Yamauchi Email: mitsuo_yamauchi@unc.edu Phone: (919) 537-3217	Other Cores at University of North Carolina at Chapel Hill	measuring collagen content and structure in biological samples visualizing collagen distribution	Collagen Analysis Core
Computer Network Recharge Center The department’s computing environment includes over 1000 computers, ranging from older systems used for generating network traffic for simulated Internet experiments to state-of-the-art workstations and clusters for graphics- and compute-intensive research.	Sara Cockerham Email: saraco@unc.edu Phone: (919) 445-6935	Other Cores at University of North Carolina at Chapel Hill	0	Computer Network Recharge Center
Computer Services Recharge Center The department’s computing environment includes over 1000 computers, ranging from older systems used for generating network traffic for simulated Internet experiments to state-of-the-art workstations and clusters for graphics- and computer-intensive research.	David Cowhig Email: dcowhig@cs.unc.edu Phone: (919) 590-6000	Other Cores at University of North Carolina at Chapel Hill	0	Computer Services Recharge Center
Cystic Fibrosis Antibody Distribution Program The Cystic Fibrosis Foundation, in conjunction with the laboratory of Dr. Jack Riordan and Dr. Martina Gentzsch of the University of North Carolina at Chapel Hill are pleased to offer anti CFTR antibodies to the cystic fibrosis research community.	Tim Jensen Email: tim_jensen@med.unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	Ultra-low temperature freezers for storing antibodies antibody storage, handling, and characterization	Cystic Fibrosis Antibody Distribution Program
Dentistry Storeroom The Preclinical Storeroom provides a pass-through purchasing program for all materials needed during the four-year course of study at the Adams School of Dentistry. The storeroom also provides any and all consumable items needed in the preclinical laboratories. These items are covered by the Student Lease Program.	Arnel Besillio Email: abasillio@email.unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	dental materials stock dentistry dental school dentist	Dentistry Storeroom
Goodman Grating Lab Spectrograph Goodman Grating Lab	Chris Clemens Email: clemens@physics.unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	0	Goodman Grating Lab Spectrograph
Health on Wheels Health on Wheels is a mobile medical unit program to bring basic health initiatives and opportunities directly to the community. The unit is available to UNC researchers, UNC clinicians and other UNC collaborators.	David Wohl Email: david_wohl@med.unc.edu Phone: (919) 843-2723	Other Cores at University of North Carolina at Chapel Hill	0	Health on Wheels
Innovate Carolina Innovate Carolina is UNC-Chapel Hill’s department for innovation, entrepreneurship and economic development that provides a full-scale hub designed for today’s problem solvers: innovation-minded faculty, students and community partners who use their ingenuity to nudge the world forward.	Cynthia Reifsnider Email: Cynthia_Reifsnider@unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	Innovation, Entrepreneurship and Economic Development technology commercialization patent patents market research innovation impact measurement	Innovate Carolina
Insect Culture Media Insect Culture Media	Jeff Sekelsky Email: sekelsky@unc.edu Phone: (919) 306-6338	Other Cores at University of North Carolina at Chapel Hill	0	Insect Culture Media
Isotope Geochemistry Lab The Isotope Geochemistry Lab at UNC Chapel Hill is a fully functional geochemistry laboratory overseen by Dr. Drew Coleman, Dr. Ryan Mills, and Dr. Paul Fullagar (emeritus). University, local, national, and international researchers regularly use the lab.	Drew Coleman Email: dcoleman@unc.edu Phone: (910) 962-0705	Other Cores at University of North Carolina at Chapel Hill	Isotope preparation equipment: Mills, digesters, clean rooms geology	Isotope Geochemistry Lab
Marine Sciences Facility Services (IMS) The Institute of Marine Sciences (IMS) is an off-campus research laboratory, teaching, outreach, and part of the University of North Carolina at Chapel Hill’s (UNC-CH) Department of Earth, Marine, and Environmental Sciences. Located on the central North Carolina coast in Morehead City; the mission of UNC’s Institute of Marine Sciences is to conduct cutting-edge research, train young scientists, provide expertise to governmental agencies and industry, and to promote new knowledge to inform public policy.	Jennifer Parker Email: jstacey@email.unc.edu Phone: (919) 966-4517	Other Cores at University of North Carolina at Chapel Hill	0	Marine Sciences Facility Services (IMS)
Marine Sciences Sample Analysis Recharge (IMS) The Institute of Marine Sciences (IMS) is an off-campus research laboratory, teaching, outreach, and part of the University of North Carolina at Chapel Hill’s (UNC-CH) Department of Earth, Marine, and Environmental Sciences. Located on the central North Carolina coast in Morehead City; the mission of UNC’s Institute of Marine Sciences is to conduct cutting-edge research, train young scientists, provide expertise to governmental agencies and industry, and to promote new knowledge to inform public policy.	Jennifer Parker Email: jstacey@email.unc.edu Phone: (919) 966-4517	Other Cores at University of North Carolina at Chapel Hill	0	Marine Sciences Sample Analysis Recharge (IMS)
Marine Sciences Scanning Sonar (IMS) The Institute of Marine Sciences (IMS) is an off-campus research laboratory, teaching, outreach, and part of the University of North Carolina at Chapel Hill’s (UNC-CH) Department of Earth, Marine, and Environmental Sciences. Located on the central North Carolina coast in Morehead City; the mission of UNC’s Institute of Marine Sciences is to conduct cutting-edge research, train young scientists, provide expertise to governmental agencies and industry, and to promote new knowledge to inform public policy.	Jennifer Parker Email: jstacey@email.unc.edu Phone: (919) 966-4517	Other Cores at University of North Carolina at Chapel Hill	0	Marine Sciences Scanning Sonar (IMS)
Multidisciplinary Simulation Laboratory The Multidisciplinary Simulation Laboratory, part of the UNC Department of Surgery, provides simulation training in surgical and medical procedures for resident physicians, medical students, physicians, nurses and surgical technologists. The center also hosts medical industry simulation training.	Neal Murty Email: neal_murty@med.unc.edu Phone: (919) 962-3125	Other Cores at University of North Carolina at Chapel Hill	CAE Healthcare SimMan 3G Medical Simulator CAE Healthcare Anesthesia Simulator ImmersiveTouch Surgical Simulator Oculus Quest 2 Virtual Reality Headset	Multidisciplinary Simulation Laboratory
NMR Helium Recovery and Liquefaction Plant NMR Helium Recovery and Liquefaction Plant	Stuart Parnham Email: stitch@email.unc.edu Phone: (919) 966-6184	Other Cores at University of North Carolina at Chapel Hill	Helium recovery and liquefaction cryopumps, Joule-Thomson expanders	NMR Helium Recovery and Liquefaction Plant
Odum Institute The mission of the Odum Institute for Research in Social Science is to foster groundbreaking social research that improves the lives of people in North Carolina and around the world.	Jessica Grant Email: jgrant1@unc.edu Phone: (919) 962-4760	Other Cores at University of North Carolina at Chapel Hill	Environmental monitoring equipment: Onset HOBO U30/U30C Temp/RH Logger, Campbell Scientific CR1000 Data Logger GIS software: ArcGIS, QGIS	Odum Institute
Oral Microbiology Core Laboratories The OML provides diagnostic clinical microbiology, microbiological research, microbiology training and sterilization monitoring services to both the school and the community of dental practitioners in North Carolina and the surrounding geographic area.	Roland Arnold Email: roland_arnold@unc.edu Phone: (919) 537-3165	Other Cores at University of North Carolina at Chapel Hill	Anaerobic chambers Coy Anaerobic Glove Box Bactron IV Anaerobic Chamber Molecular biology equipment Thermo Scientific GeneJET PCR Kit Bio-Rad Gel Electrophoresis System NanoDrop 1000 Spectrophotometer Nikon Eclipse Ti2 Inverted Microscope Heraeus HeraCell 1500 CO2 Incubator Microbiology Autoclave Centrifuge	Oral Microbiology Core Laboratories
Physics Maintenance Shop The Physics and Astronomy instrument shop provides complete professional instrument construction for research at UNC. It is located in Phillips Hall room 115.	Philip Thompson Email: philip@email.unc.edu Phone: (919) 962-1183	Other Cores at University of North Carolina at Chapel Hill	Design consultation CNC machining Electric discharge Welding Sheet metal fabrication Plastic fabrication CAD SLDPRT, IGES, and STP	Physics Maintenance Shop
Serology Service Center Serology Service Center	Prem Lakshmanane Email: prem@med.unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	0	Serology Service Center
Sheps Data Analytics, Web and Database Programming, and Research Computing Services The Cecil G. Sheps Center for Health Services Research seeks to improve the health of individuals, families, and populations by understanding the problems, issues, and alternatives in the design and delivery of health care services.	Brian Cass Email: brian.cass@unc.edu Phone: Please email.	Other Cores at University of North Carolina at Chapel Hill	Data storage and management systems: SAN, NAS Data analysis software: SAS, R, Python Web development software: HTML, CSS, JavaScript Database programming software: MySQL, Oracle, SQL Server High-performance computing (HPC) cluster: Dell PowerEdge servers, NVIDIA GPUs	Sheps Data Analytics, Web and Database Programming, and Research Computing Services

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
CryoEM Core Provide assistance in all aspects of high-resolution cryo-electron microscope. To include specimen preparation, data collection, and image processing. We provide training, technical advice, and consultations for users interested in learning cryoEM.	Joshua Strauss Email: Joshua_Strauss@med.unc.edu Phone: (919) 962-5526	Structural Biology and Chemistry	200 kV Thermo Fisher Scientific Talos Arctica electron microscope Vitrobot Mark IV cryo-plunger Gatan K3 direct electron detector	CryoEM Core
High Throughput Peptide Synthesis and Array Core Facility We use automated Fmoc SPPS to make synthetic peptides. We are routinely making 20-30-mer peptides, but also have experience with synthesis of longer sequences, 40-60-mer. Homogeneity is evaluated by mass analysis (MALDI-TOF MS) and analytical HPLC.	Krzystof Krajewski Email: kka@email.unc.edu Phone: (919) 843-3935	Structural Biology and Chemistry	Peptide synthesizers: Symphony multiple peptide synthesizer, PS-3 peptide synthesizer HPLC systems: Waters preparative, semi-preparative, and analytical HPLC instruments Microarray printer: GeneMachines OmniGrid 100 Microarray Printer VirTis BenchTop Lyophilizers with Speed-Vac	High Throughput Peptide Synthesis and Array Core Facility
Macromolecular Interactions Facility The Macromolecular Interactions Facility (UNC folks fondly call it the Mac-In-Fac) is a core facility of the University of North Carolina at Chapel Hill. It provides instrumentation & resources for biophysical characterization of biological macromolecules and their interactions with cognate ligands.	Ashutosh Tripathy Email: ashutosh_tripathy@med.unc.edu Phone: (919) 962-4399	Structural Biology and Chemistry	Biacore 8K Surface Plasmon Resonance (SPR) Malvern Panalytical ITC200 Isothermal Titration Calorimetry (ITC) Octet Red384 SPR NanoDrop One Spectrophotometer Eppendorf Multipette E4 epipette Eppendorf Mastercycler Nexus Gradient PCR	Macromolecular Interactions Facility
Macromolecular X-Ray Crystallography Facility The UNC Crystallography Core Facility provides support and infrastructure necessary to enable investigators to initiate and complete a structural biology or structural chemistry project. Services include crystallization, x-ray diffraction data collection, and structure determination and refinement.	Nathan Nicely Email: nnicely@email.unc.edu Phone: (919) 843-7174	Structural Biology and Chemistry	Rigaku Jupiter X-ray diffractometer Rigaku MiniFlex 600 X-ray diffractometer Bruker D8 Venture X-ray diffractometer Dectris Pilatus 2M detector Oxford Instruments Cryostream 700+ cryostat	Macromolecular X-Ray Crystallography Facility
Molecular Biology Core - Marsico Lung Institute Molecular biology has become an indispensable component of modern biological research programs. The Molecular Biology Core was established to provide expertise, equipment, training, and reagents to serve the molecular biology needs for the Marsico Lung Institute/UNC Cystic Fibrosis Center.	Wanda O'Neal Email: woneal@med.unc.edu Phone: (919) 962-9866	Structural Biology and Chemistry	Thermo Fisher Scientific QuantStudio 7 Pro Real-Time PCR System Agilent 2100 Bioanalyzer Qubit 4 Fluorometer Bio-Rad Gel Doc EZ Imaging System	Molecular Biology Core - Marsico Lung Institute
Mucus Biochemistry/Biophysics Core The mucus clearance system of the lung represents a key innate defense system that protects the airway surface against constant exposure to inhaled infectious and noxious particles. Abnormal clearance of mucus is an important contributor to the phenotype of patients with chronic bronchitis (CB).	Brian Button Email: brian_button@med.unc.edu Phone: (919) 966-5823	Structural Biology and Chemistry	Anton Paar MCR 302 Rheometer TA Instruments Discovery HR-2 Rheometer Lauda Viscomatic EL Viscometer Biolin Scientific Attension Theta Optical Tensiometer	Mucus Biochemistry/Biophysics Core
NMR - UNC Biomolecular NMR Laboratory The UNC Biomolecular NMR Laboratory was created to support research into the structure and dynamics of biological molecules. The Biomolecular NMR Lab offers a variety of services to academic and industrial users. We are happy to work with users from outside UNCCH to support their research needs.	Stuart Parnham Email: stitch@email.unc.edu Phone: (919) 966-6184	Structural Biology and Chemistry	Nuclear magnetic resonance (NMR) spectrometers (up to 900 MHz): Varian Inova 900, Bruker Avance III 900 Cryogenics equipment: liquid helium dewars, superconducting magnets NMR data analysis software: NMRPipe, TopSpin	NMR - UNC Biomolecular NMR Laboratory

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Human Pluripotent Stem Cell Core The purpose of the Human Pluripotent Cell Core Facility is to provide UNC scientists as well as outside collaborators with the services to successfully conduct basic as well as translational research using human induced pluripotent cells.	Adriana Beltran Email: beltran@med.unc.edu Phone: (919) 537-3995	Tissue and Cell Culture	Cell culture equipment: CO2 incubators, sterile hoods, centrifuges Flow cytometers: BD FACSAria II, BD FACSCalibur Pluripotency assays: Alkaline phosphatase staining, immunofluorescence staining, teratoma formation assays	Human Pluripotent Stem Cell Core
Tissue Culture Facility Our facility supplies almost any medium, reagent, additive or consumable item required in cell culture and molecular biology research at a deep discount with prompt on-site availability. TCF also has an extensive cell line repository.	Amy Patrylick Email: tcf@med.unc.edu Phone: (919) 966-1034	Tissue and Cell Culture	Cell culture reagents: Fetal bovine serum, antibiotics, trypsin	Tissue Culture Facility
Tissue Procurement and Cell Culture Core - Marsico Lung Institute We provide standardized cell cultures for cystic fibrosis (CF) research. The Core serves as a central source of normal, CF and disease control cells, tissues and fluids for a wide array of uses.	Leslie Fulcher Email: Leslie_Fulcher@med.unc.edu Phone: (919) 966-7055	Tissue and Cell Culture	Leica CM1950 Cryostat BD Biosciences Aria II Cell Sorter Thermo Fisher Scientific Forma SterilGARD eCO2 Incubator Nuaire Biological Safety Cabinets	Tissue Procurement and Cell Culture Core - Marsico Lung Institute

Core Name - Description	Primary Contact	Category	Keywords	Core Sort
Lenti-shRNA Core Facility The Lenti-shRNA Core Facility is premised in Open Biosystems TRC1 shRNA libraries. The libraries are cataloged as a single lentiviral-vector shRNA expression clones directed to +/- 16,000 human and mouse genes. Each gene is targeted by 4 or 5 different shRNAs driven by the U6 promoter.	Tal Kafri Email: tal_kafri@med.unc.edu Phone: (919) 843-7635	Vector Production	Lentiviral vector production Lentiviral transduction shRNA library PCR Flow cytometers Fluorescence microscopes	Lenti-shRNA Core Facility
NeuroTools Core We provide full spectrum support for the production and use of viral tools in neuroscience applications.	Kim Ritola Email: neurotools@unc.edu Phone: (919) 445-1711	Vector Production	Stereotaxic equipment: Kwik-Stage, David Kopf Electrophysiology equipment: Axopatch 200B amplifiers, MultiClamp 700B amplifiers Behavioral testing equipment: Noldus Ethovision software, Med Associates testing chambers Optogenetics equipment: ChR2/EYFP mice, Optogenetics laser systems Animal surgery and imaging equipment: Leica microscopes, IVIS Spectrum imaging system	NeuroTools Core
Vector Core The Vector Core at the University of North Carolina at Chapel Hill (UNC Vector Core) was founded in 1993 as a full-service viral vector production organization. We have extensive experience in manufacturing research grade vectors utilize our unique expertise to ensure your project is on time and on budget. Our goal is to deliver the highest quality AAV vectors to our academic, government, foundation, and biotech industry clients.	Xinghua Zeng Email: xhzeng@med.unc.edu Phone: (919) 445-0338	Vector Production	Molecular biology equipment: PCR machines, gel electrophoresis systems, centrifuges DNA cloning Plasmid kits, restriction enzymes, ligases Cell transfection equipment: Electroporators, lipofectamine reagents Viral vector production equipment: Bioreactors, cell culture equipment Viral vector analysis equipment: ELISA kits, flow cytometry analyzers	Vector Core

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NEGOTIATED RATES	On-Campus	Off-Campus < 10-mile	Off-Campus ≥ 10-mile
Organized Research	55.5%	28%	26%
Instruction	50%	28%	26%
Other Sponsored Activities	36%	28%	26%